Principal investigator- Assay Biology

Job Description

Designation: Prinicipal Investigator- Assay BiologyJob Location: BangaloreDepartment: Discovery BiologyAbout SyngeneLooking for a highly innovative, enthusiastic and result-oriented individual who will lead a team of scientists, interfacing with the clients for their research and business needs and managing the activities of the Assay Development Group complying with the company quality and regulatory standards. The candidate will be involved in guiding the team for the development & qualification of different types of cell based and biochemical assays as part of the integrated and standalone projects.Job PurposeIn this role, the successful candidate will provide strong scientific, operational and strategic leadership to multiple teams in Leading In Vitro ADME group and develop high performing teams with innovative thinking. Ability to lead larger teams (>25 scientists) and mentor staff with highest scientific excellence in the In Vitro ADME space. Interacting with cross functional scientific teams & external collaborators & remain as a subject matter expert in the In Vitro ADME services. DMPK co-lead project lead role to support integrated drug discovery programmes.Key Responsibilities

• Scientifically contributing and leading the client FTE projects, regular updates and communications to internal and external customers on the progress of the project
• Manage a team of Scientists- Masters [includes goal setting, understanding developmental needs, assigning responsibilities in the laboratory activities, critically assessing their performance and providing timely feedback]
• Scientific execution of work, developing new assays, troubleshooting the assays, data analysis and presentations
• Active participation in the strategic drives- Data Integrity and Safety; Compound management & automation based on experience
• Writing and Review of Laboratory Note Books, Raw data and study report to ensure data integrity for himself/herself and for reporting team.
• Review reports and protocol of method development, qualification, and other studies
• Responsible for detailed planning of sample analysis and execution of protocol based studies.
• Technical data presentation in departmental and functional meetings.
• Maintains compliance with all company policies and procedures.
• Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
• Ensuring that there are no safety non-compliances in areas that my team operates in.
• Ensuring adherence to all Syngene policies related to data integrity by all members of the team including self
• Ensuring all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
• Reporting incidents (or near-misses) and learnings from those incidents to avoid recurrence.
• Compliance to Syngene s quality standards at all times and ensuring the same by the team members.

Educational Qualification: PhD in a relevant discipline and 6 to 9 years of relevant industry (CRO, Pharma or Biotech) experience. Proven track record preferably in a contract research environment would be desirable.Technical/functional Skills:

• Subject area (therapeutic area) expertise and in-depth technical understanding of drug discovery.
• Experience with different target classes, MoA studies with small and/or large molecules and developing miniaturized cell based assays, biophysical and biochemical assays.
• Experience with cell based assays in cell lines, reporter lines, primary cells pertaining to different disease indications
• Interacts with other members of the department in developing innovative technologies and assay platform.
• Knowledge in regulatory guidelines related to biosafety, and statistical data analysis.

Behavioral Skills:

• Demonstrate strong people management skills, leading by example with a high level of emotional intelligence, and be willing to work collaboratively with other functional groups.
• Excellent interpersonal, communication and presentation skills. Ability to lead cross-functional teams and act as a true team player.
• Ability to discuss and debate data and project strategy with demanding clients and scientific experts.

Equal Opportunity Employer:It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individuals with disabilities.,

Keyskills :
compliancecell based assaysresearchclient handlingprimary cellsin vitrocell linesequal employment opportunitychemistrycorepeople management skillsmusic makingdata integritydata analysis