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Associate Scientist - Downstream Process Development

5.00 to 9.00 Years   Delhi   09 Dec, 2022
Sygene
Job LocationDelhi
EducationNot Mentioned
SalaryNot Disclosed
IndustryPharma / Biotech
Functional AreaBio Tech / R&D / Scientist
EmploymentTypeFull-time

Job Description

    Overall adherence to safe practices and procedures of oneself and the teams aligned Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company s integrity & quality standards Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times. Ensuring safety of self, teams, and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace. Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self Compliance to Syngene s quality standards at all times Hold self and their teams accountable for the achievement of safety goals Govern and Review safety metrics from time to timeJob Purpose: The role is responsible to downstream process development.Key Responsibilities: Support designing and execution of experiments to develop a scalable purification process. Should have knowledge of protein chemistry, preparative chromatography and/or membrane separation techniques to develop manufacturing process of biologics. Should be able to draft experimental protocol and getting it reviewed by the team lead. Execution of the laboratory experiments and documenting them in detail in laboratory notebook and in soft copies. Forecasting of material required in a given project where he/she has been assigned a role. General lab maintenance and inventory management. The individual could also be expected to perform analytical assays, analyze and present research data within the department. Understand technical instructions and able to execute/guide the fellow executive in Downstream process development experiments. Analyze and interpret data. Discuss with Team Leader and other team members to deciding action plans. Update the Team Leader, Group Leader, Department Head, Project Leader and Program Management Coordinator and help monitor the progress of the project against established timelines.Educational Qualification: Master s degree in BiotechnologyTechnical/functional Skills: Overall, knowledge of downstream unit operations for large molecule is must. Preferred candidate should have worked on Mammalian cell culture derived mAb and/or non-mAb protein. Should be conversant with interpretation of analytical and process data (e.g. proteins). Should be conversant with downstream process Scale-Up principles and have been involved in at least one scale-up related activity. Should be conversant with QbD principles and developed process using DoE approach Proficient in handling of Chromatographic systems Possess good communication skills (written and oral Communication), Good at documentation skills (Report Preparation, SOPs, etc) Should possess a sound knowledge of operating Tangential flow filtration and interpreting experimental results using standard tools. Should be proficient in MS excel.Experience: 5-9 years of experience,

Keyskills :
sopvalidationprotocolshplcdata integritydocumentationmammalian cell culture

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