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Senior Research Associate-Protein Purification

1.00 to 4.00 Years   Delhi   11 Apr, 2022
Syngene International Limited
Job LocationDelhi
EducationNot Mentioned
SalaryNot Disclosed
IndustryEducation / Training
Functional AreaBio Tech / R&D / Scientist
EmploymentTypeFull-time

Job Description

    Designation: Senior Research Associate - Protein Purification Job Location: Bangalore Department: Discovery Biology About Syngene Incorporated in 1993, Syngene International Ltd. is an innovation-focused global discovery, development and manufacturing organization providing integrated scientific services to the pharmaceutical, biotechnology, nutrition, animal health, consumer goods and specialty chemical industries around the world. Syngene s clientele includes world leaders such as Bristol-Myers Squibb, Baxter, Amgen, GSK, Merck KGaA and Herbalife. Its innovative culture is driven by the passion of its 4240- strong team of scientists who work with clients from around the world to solve their scientific problems, improve R&D productivity, speed up time to market and lower the cost of innovation. Job Purpose: The incumbent will perform protein purification and characterization from various expression systems. Key Responsibilities:
    • Independently perform protein purification from various expression systems Mammalian, E. coli & Insect cell) and QC.
    • Prepare detailed reports for sharing with clients and attend telecons. Improve lab efficiency and streamlines the operational processes to increase productivity. Analyze operational problems, identify solutions, and implement corrective actions. Guide and train research scientists in the team at various levels.
    • Understanding and demonstrating responsibility for safety of self & colleagues by following all safety protocols provided by Syngene
    • Adherence to all environment, health, and safety (EHS) policies & standards at all times in the workplace
    • Wearing all PPE as required.
    • Adherence to all procedures related to Syngene s data integrity policies
    • Compliance to Syngene s quality standards at all times.
    Educational Qualification: Candidate with a MSc/MTech in Life sciences Technical/functional Skills:
    • Expertise in routine protein purification with affinity, size exclusion, ion exchange chromatography using AKTA FPLC systems (Unicorn software).
    • Expertise in protein purification of antibodies, affinity-tagged, secreted proteins as well as problematic proteins (low expression, poor solubility, intra-cellular expression, prone to aggregation).
    • Proficiency in protein extraction and solubilization methods, protein refolding and purification via affinity, hydrophobic interaction (HIC), ion exchange (IEX), size exclusion (SEC) and mixed-mode chromatography.
    • Expertise in routine characterization of proteins including SDS-PAGE, SE-HPLC, and biophysical techniques.
    • Familiarity with mammalian and microbial protein expression is a plus.
    Experience: 1-4 Years Post qualification Behavioral Skills:
    • Take accountability and ownership for respective job function maintain data integrity & exhibit good data management skills.
    • Excellent attention to details, diligent documentation and efficient communication skills
    Equal Opportunity Employer: It is the policy of Syngene to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by applicable legislation or local law. In addition, Syngene will provide reasonable accommodations for qualified individualswith disabilities. ,

Keyskills :
nmrresearchhplcequal employment opportunityanimal healthvalidationliterature

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